Filgrastim

 Filgrastim

Filgrastim usually given SQ, the brand name is neupogen. It is man-made form of granulocyte colony-stimulating factor(G-CSF). G-CSF is a substance produced by the body. It stimulates the growth of neuropils which is one of white blood cells fighting against infection. Filgrastim used myelosuppressive chemotherapy give through subcutaneous (300mcg/ml ) 5mcg/kg/d no earlier than 24 hours before next dose of chemotherapy, dose given  daily for up to 2 weeks, discontinue if ANC >10000 mm3 after expected nadir or chemotherapy. CBC counts must monitored closely (Woo & Robinson, 2020).