The Emergence of Mass Spectrometry in Biochemical Research Discussion

The Emergence of Mass Spectrometry in Biochemical Research Discussion

read the paper then please answer the following questions each one in separate answer

What is the primary difference between MALDI and ESI with respect to charge state generation?

What is the role of H/D exchange in biological mass spectrometry (i.e. what does it tell you)?

What two classes of biopolymers can be sequenced using MALDI and ESI combined with tandem MS?